Biochim Biophys Acta 2003, 1653: 1–24.PubMed 5. Nelson J, Nusse R: Convergence of Wnt, β-catenin, and cadherin pathways. Science 2004, 303: 1483–1487.PubMedCrossRef 6. Veeman MT, Axelrod JD, Moon RT: A second canon. Functions and mechanisms of β-catenin-independent Wnt signaling. Dev Cell 2003, 5: 367–377.PubMedCrossRef 7. Miller JR: The Wnts. Genome Biol 2002, 3: REVIEWS3001.PubMed 8. Kawano Y, Kypta R: selleck screening library Secreted antagonists of the Wnt signaling pathway. J Cell Sci 2003, 116: 2627–2634.PubMedCrossRef 9. Zorn AM: Wnt signalling: antagonistic Dickkopfs.
Curr Biol 2001, 11: R592-R595.PubMedCrossRef 10. Bafico A, Liu G, Yaniv A, Gazit A, Aaronson SA: Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow. Nat Cell Biol 2001, 3: 683–686.PubMedCrossRef 11. Semenov MV, Tamai K, Brott BK, Kühl M, Sokol S, He X: Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6. Curr Biol 2001, 11: 951–961.PubMedCrossRef SN-38 chemical structure 12. Mao B, Wu W, Li Y, Hoppe D, Stannek P, Glinka A, Niehrs C: LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature 2001, 411: 321–325.PubMedCrossRef 13. Mao B, Wu W, Davidson G, Marhold J, Li M, Mechler BM, Delius H, Hoppe D, Stannek P, Walter C, Glinka
A, Niehrs C: Kremen proteins are Dickkopf receptors that regulate Wnt/β-catenin signaling. Nature 2002, 417: 664–667.PubMedCrossRef Methamphetamine 14. Rothbacher U, Lemaire P: Crème de la Kremen of Wnt signaling inhibition. Nat Cell Biol 2002, 4: E172–173.PubMedCrossRef 15. Mikheev AM, Mikheeva SA, Liu B, Cohen P, Zarbl H: A functional genomics approach for the identification of
putative tumor suppressor genes: Dickkopf-1 as suppressor of HeLa cell transformation. Carcinogenesis 2004, 25: 47–59.PubMedCrossRef 16. Lois DN, Ohgaki H, Wiesfler OD, et al.: World organization classification of tumors of the central Rigosertib nmr nervous system. Lyon: International Agency for Research on Cancer (IARC) Press; 2007. 17. Yamabuki T, Takano A, Hayama S, Ishikawa N, Kato T, Miyamoto M, Ito T, Ito H, Miyagi Y, Nakayama H, Fujita M, Hosokawa M, Tsuchiya E, Kohno N, Kondo S, Nakamura Y, Daigo Y: Dikkopf-1 as a novel serologic and prognostic biomarker for lung and esophageal carcinomas. Cancer Res 2007, 67: 2517–2525.PubMedCrossRef 18. Krupnik VE, Sharp JD, Jiang C, Robison K, Chickering TW, Amaravadi L, Brown DE, Guyot D, Mays G, Leiby K, Chang B, Duong T, Goodearl AD, Gearing DP, Sokol SY, McCarthy SA: Functional and structural diversity of the human Dickkopf gene family. Gene 1999, 238: 301–313.PubMedCrossRef 19. Politou MC, Heath DJ, Rahemtulla A, Szydlo R, Anagnostopoulos A, Dimopoulos MA, Croucher PI, Terpos E: Serum concentrations of Dickkopf-1 protein are increased in patients with multiple myeloma and reduced after autologous stem cell transplantation. Int J Cancer 2006, 119: 1728–1731.PubMedCrossRef 20.