Twenty prospective energetic components of UR and 24 prospective active components of EC had been correspondingly collected, and 92 anti-hypertensive possible targets of UR-EC were gotten. According to FunRich enrichment outcomes, the optimal sign of UR-EC was pregnancy hypertension, which involved calcium signaling pathway, HIF-1 signaling pathway, neuroactive ligand receptor communication, renin vascular tightening, VEGF signaling pathway, etc. In addition, AKT1, NOS2, ADRB2, F2, NOS3, SCN5 A, HTR2 A and JAK2 were regarded as the main element goals when you look at the network. The molecular docking results showed that the screened potential energetic elements had high binding activity using the crucial goals. This study preliminarily disclosed that UR-EC might have therapeutic results on maternity high blood pressure with regards to sedation, anti-hypertension, anti-inflammatory, anti-oxidation, enhancement of vascular endothelial purpose and so forth.Hypertension is a kind of persistent aerobic system illness caused by a number of elements and carriers dysfunction, which is one of the sounding Tibetan medicine "Chalong disease", and it has a higher rate of impairment and death. Zuomua Decoction is a classical Tibetan medicine for Chalong illness, but its method just isn’t clear. Therefore, in this paper we explored the multi-components, multi-targets and multi-channels method of Zuomua Decoction within the remedy for high blood pressure considering community pharmacology and molecular docking technology. First of all, the chemical aspects of Zuomua Decoction had been gotten into the retrieval of standard Chinese medicine systems pharmacology database(TCMSP), Asia National Knowledge Infrastructure(CNKI) and Wanfang database. The potential objectives of Zuomua Decoction were predicted by BATMAN-TCM database, and also the targets of hypertension had been gotten simply by using DisGeNET database. The intersection of those two targets set was taken up to have the potentiein interaction community, as well as in the comprehensive evaluation, it had been found that Zuomua Decoction could decrease blood pressure levels by regulating renin angiotension aldosterone system, managing the focus of intracellular calcium and salt ions and regulating vasoconstriction and relaxation. ACE, AGTR1, and ADRB2 were utilized as the companies for molecular docking study from the aspects of Zuoma Decoction, as well as the results showed that the chemical components of Zuomua Decoction had a beneficial binding task with key goals. The objective of this study is to provide tips when it comes to in-depth study of Zuoma Decoction within the remedy for high blood pressure, and supply clinical foundation for the clinical rational application.This paper directed to research the active components and process of Taohong Siwu Decoction when you look at the remedy for major dysmenorrhea(PD) according to system pharmacology and molecular docking technology. Conventional Chinese Medicine techniques Pharmacology Database and Analysis Platform(TCMSP) had been utilized to find the chemical compositions and goals of six natural herbs in Taohong Siwu Decoction. The objectives for PD treatment had been chosen through the databases of DrugBank, OMIM, TTD and CTD, and gene annotation of this goals had been performed with UniProt database. Cytoscape 3.7.2 was then used to construct the drug-compound-target community. The protein-protein interaction(PPI) system had been built considering STRING, while the core goals of Taohong Siwu Decoction when you look at the remedy for PD were selected in accordance with the topological variables. David database ended up being utilized for GO enrichment analysis and KOBAS 3.0 was useful for KEGG enrichment analysis. The molecular docking technology had been made use of to get in touch the components with higher medium values into the community selleckchem with core goals. The results indicated that the system contained 36 compounds such as quercetin, kaempferol, luteolin, myricanone and ferulic acid, and 99 targets such as PTGS2, PTGS2, PGR and PPARG. Totally 102 GO terms had been gotten by GO practical enrichment analysis(P<0.01), and 228 sign paths had been acquired by KEGG path enrichment(P<0.05), primarily concerning inflammatory factors, hormones regulation, central analgesia, amino acid metabolic process and spasmolysis. The outcomes of molecular docking revealed that the key active components can spontaneously bind to your objectives immune status . This research preliminarily unveiled the apparatus of Taohong Siwu Decoction for remedy for main dysmenorrheal through multi-components, multi-targets and multi-pathways, supplying theoretical references for additional researches on system of Taohong Siwu Decoction.To explore the procedure of Sijunzi Decoction into the treatment of ulcerative colitis(UC) according to network pharmacology. The energetic elements and corresponding goals of Sijunzi Decoction had been transmediastinal esophagectomy extracted with Traditional Chinese Medicine Systems Pharmacology Database and review Platform(TCMSP), plus the targets had been standardized by using Uniprot database. The associated targets of UC were acquired through GeneCards database and Disgenet database, and the intersection targets of medications and conditions had been screened by R language. The artistic legislation network of "active ingredient-disease target" of Sijunzi Decoction was constructed by Cytoscape computer software, and the protein-protein interacting with each other system was constructed by STRING database. The useful enrichment evaluation of gene ontology(GO) and the enrichment analysis of Kyoto encyclopedia of genes and genomes(KEGG) path were done on Bioconductor platform, plus some for the targets had been verified by animal experiments. Through database analysi the phrase of IL-6 and caspase-3, and having taking part in apoptosis, infection and other pathways.This article analyze acupoint choice and faculties of plaster therapy for stable chronic obstructive pulmonary di-sease(COPD) by information mining. The CNKI, VIP, CBM, WanFang, PubMed, EMbase, Cochrane Library were retrieved for collecting clinical scientific studies of plaster therapy for stable COPD. After literary works screening, a complete of 46 systematic reviews had been included. Frequency statistics, group analysis, and Apriori correlation analysis were utilized to investigate the design and characteristics of plaster therapy for steady COPD. The effect indicated that the primary acupoints for stable COPD were BL13, Dingchuan, CV22, BL23 and BL20. The acupoints used are mainly focused regarding the upper body and right back.