Men without lamina dura with radiolucency showed significantly more tooth loss than those with a lamina dura without radiolucency (P < 0.00001) and those without a lamina dura without radiolucency (P. 0.0001), indicating the influence of poor oral health. Thus, the phenomenon without a lamina dura without radiolucency may show the clinical importance of bone formation in the elderly.”
“Objective-To evaluate effects of vaccination with a killed whole-cell vaccine against Mycobacterium avium subsp paratuberculosis (MAP) on fecal shedding of the organism, development of clinical paratuberculosis (Johne’s disease [JD]), milk production, measures of reproduction, and within-herd longevity of dairy cattle naturally
exposed to MAR
Design-Controlled clinical trial.
Animals-200 vaccinated and 195 unvaccinated AZD7762 (control) dairy cows from 3 herds in Wisconsin.
Procedures Every other heifer calf born in each herd received the MAP vaccine; 162 vaccinates and 145 controls that had >= 1 lactation were included in analyses. Bacteriologic culture of fecal samples for MAP was performed annually for 7 years; results were confirmed via histologic methods and PCR assay. Production records and culture results were evaluated to determine effects of vaccination
on variables of interest in study cows. Annual whole-herd prevalence of MAP shedding in feces was also determined.
Results-Vaccinates had a significantly lower hazard of testing positive for MAP via culture of fecal samples than did controls over time (hazard ratio, 0.57; 95% confidence interval, 0.34 to 0.97). Fewer vaccinates developed clinical JD than did controls (n = 6 and see more 12, respectively), but these differences were nonsignificant. Overall within-herd longevity, total milk production, and calving-to-conception intervals were similar PD-1/PD-L1 Inhibitor 3 inhibitor between vaccinates
and controls. In all herds, prevalence of MAP shedding in feces decreased over time.
Conclusions and Clinical Relevance-Vaccination with a killed whole-cell MAP vaccine appeared to be an effective tool as part of a program to control the spread of JD in dairy cattle. (J Am Vet Med Assoc 2013;242:663-669)”
“Purpose: To study track structure effects in cells irradiated by heavy ions, we have performed a model analysis of an extensive recently published data set of over 40 survival curves of normal human skin fibroblast cells irradiated in vitro by energetic carbon, neon, silicon and iron ions measured in track-segment conditions.
Materials and methods: Having derived the required track-segment descriptions of the ion bombardments from the published data, we fitted four parameters of the cellular track structure theory (Katz model) to the whole data set.
Results: Using track structure calculations with the best-fitted parameters, we demonstrate a systematic interpretation of this data set, highlighting effects specific to track structure.