In controls, tissue samples were obtained immediately after tooth extraction scheduled for orthodontic reasons. Clinical parameters included probing depth, clinical attachment level, Caspase pathway gingival

index, bleeding index, plaque index. SOD activities were assessed spectrophotometrically at baseline and 2 months post NSPT, results were analysed statistically.

RESULTS: At baseline, patients with chronic periodontitis had higher mean SOD activity (2.73 +/- 1.36) than the control subjects (1.12 +/- 1.13) with p = 0.00003 (p < 0.05). At 2 months post NSPT median SOD level (1.00) had come close to median SOD value of control group (0.85); p = 0.99 (p > 0.05). The resolution of inflammation with successful NSPT resulted in decreased SOD levels as in control group. Clinical parameters in patients with chronic periodontitis showed a significant improvement 2 months post NSPT (p < 0.05).

CONCLUSION: Non-surgical periodontal therapy significantly improves the clinical parameters and restores previously increased SOD levels to normal in chronic periodontitis patients.”
“Study Design. Retrospective review of a prospectively collected, multicentered database from the Scoliosis Research Society.

Objectives. To

evaluate incidences of complications in a series of spinal fusions for Scheuermann kyphosis (SK) and to assess whether the incidence of complications is associated with patient age and surgical approach.

Summary of Background Data. Although there is some evidence that adolescents have lower complication rates selleck for spinal deformity surgery, this has not been well-documented for SK. Moreover, there is 3-deazaneplanocin A cost a lack of consensus on surgical approach for the management of SK.

Methods. The Scoliosis Research Society morbidity and mortality database was queried to identify cases of SK from 2001 to 2004. Complications rates were analyzed based on patient age and surgical approach. Pediatric and adult patients were defined as <= 19 and > 19 year old, respectively.

Results. A total of 683 procedures involving spinal fusion for SK were identified. Mean patient age was 21 years ( range: 5-75 years),

with the majority (73%) of patients <= 19 years old. Procedures included 338 (49%) posterior spinal fusions (PSF), 73 (11%) anterior spinal fusions (ASF), and 272 (40%) same-day ASF and PSF. Ninety-nine complications were reported (14%). The most common complication was wound infection (3.8%). The acute neurologic complication rate was 1.9%, including 4 spinal cord injuries (0.6%). The mortality rate was 0.6%. Complications were more common among adult (22%) compared with pediatric patients (12%) (P = 0.002). The overall incidence of complications did not differ significantly between the PSF (14.8%) and same-day ASF/PSF (16.9%) procedures (P = 0.5).

Conclusion. The incidence of complications associated with spinal fusion for SK in adults is significantly greater than in pediatric patients.