9–23.4) with overall graft survival of 87% at 5 years and 56% at 10 years (Figure 1). Five year graft survival at our institution is 85.3% for all patients. One patient developed liver cirrhosis more than 10 years after their
transplant. Most had transient rises in transaminases which usually coincided with an increase in hepatitis viral load, heralding lamivudine resistance. Of the 6 patients who died sepsis was the https://www.selleckchem.com/products/sorafenib.html cause of death in 5. The median time to death was 7.1 years (6.5–21.7). Hepatology follow-up was variable. Conclusion: Renal graft and patient survival in recipients with pre-transplant hepatitis B surface antigen positivity was comaprable to those were not infected. Liver outcomes were also acceptable but more robust guidelines would be of benefit. RUNGTA ROHIT, RAY DEEPAK SHANKAR, DAS PRATIK, GUPTA SOUMAVA Rtiics, Kolkata Introduction: Renal allograft transplantation is a well recognized modality of renal replacement therapy in patients of End Stage Renal Disease. Following transplantation ITF2357 manufacturer the recipients are usually under heavy immunosuppressants consisting of various drugs to prevent rejection of the graft. The immunocompromised
individual (recipient) is prone to various opportunistic infections and even a flare of a dormant infection apart from graft dysfunction. Re-admission following a successful transplantation is prevalent, being attributable to various causes thereby increasing the morbidity (with/without graft dysfunction) and mortality in the recipients. Methods: In this study we aim to find out the various causes, mean duration of hospital stay and the eventual fate of patients requiring readmission following transplant
within one year of the surgery. It is a retrospective study carried out in the department of Nephrology, RTIICS, kolkata, India between Jan 2009 to December 2013. All recipients who had to be admitted to our hospital within one year post transplantation were included in the study. All these patients were on three drug immunosuppresant regimens. The data thus obtained were calculated and analyzed. Results: Amongst the 240 renal transplantation that were done during the study period 35 patients (14.5%) required Cyclic nucleotide phosphodiesterase admission within the first year. Amongst these 12 (0.5%) patients required admission more than once. The various causes of admission were Diagnosed Graft dysfunction = 12 (34.2%) Pyrexia of unknown etiology = 2 (0.05%) Urinary tract infections = 18 (51%) Lower respiratory tract infections:16 (45%) Wound Infection:2 (0.05%) Other surgical causes (viz.urine leak, wound gaping etc):3 (0.08%) Surgical maneuver was needed in 3 (0.8%) patients. The mean duration of hospital stay was 22.4 days with standard deviation of 2.1. Serum level of Tacrolimus was raised in: 21 (60%) patients. we lost 3 patients due to underlying infection during the period. Conclusion: The admission rates showed univariate logistic regression with the time period post surgery (in months).